Gait after spinal cord injury and the central pattern generator for locomotion
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چکیده
منابع مشابه
Serotonin modulates the central pattern generator for locomotion in the isolated lamprey spinal cord.
The central pattern generator for locomotion in the spinal cord of the lamprey can be activated in vitro by the addition of D-glutamate to the bathing saline. Serotonin has no effects when bath-applied alone, but it modulates the D-glutamate-activated swimming pattern. Three major effects are observed: a dose-dependent reduction in the frequency of rhythmic ventral root burst discharge; enhance...
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The re-expression of hindlimb locomotion after complete spinal cord injuries (SCIs) is caused by the presence of a spinal central pattern generator (CPG) for locomotion. After partial SCI, however, the role of this spinal CPG in the recovery of hindlimb locomotion in the cat remains mostly unknown. In the present work, we devised a dual-lesion paradigm to determine its possible contribution aft...
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متن کاملThe mammalian central pattern generator for locomotion.
At the beginning of the 20th century, Thomas Graham Brown conducted experiments that after a long hiatus changed views on the neural control of locomotion. His seminal work supported by subsequent evidence generated largely from the 1960s onwards showed that across species walking, flying, and swimming are controlled largely by a neuronal network that has been referred to as the central pattern...
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The overall goal of this work is to develop the core framework for an implantable neuroprosthetic device that can restore locomotion after a severe spinal cord injury (SCI) causes paralysis. Our approach to this problem relies on a combination of the biological central pattern generator (CPG) for locomotion and an artificial silicon CPG. In particular, we propose that an artificial CPG can be u...
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ژورنال
عنوان ژورنال: Spinal Cord
سال: 1999
ISSN: 1362-4393,1476-5624
DOI: 10.1038/sj.sc.3100886